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The second carbon of the cyclohexanone radical is asymmetrical. Ketalar ® is the racemic mixture (optically inactive) of 2 enantiomers of equal quantity (isomers that diverge light in opposite ways). The active enantiomer is S(+)‐ketamine ("S" spatial structure, light diverged to the right), two times stronger than the racemic form, and.
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WHEN KETALAR IS USED ON AN OUTPATIENT BASIS, THE PATIENT SHOULD NOT BE RELEASED UNTIL RECOVERY FROM ANESTHESIA IS COMPLETE AND THEN SHOULD BE ACCOMPANIED BY A RESPONSIBLE ADULT. DESCRIPTION KETALAR is a nonbarbiturate general anesthetic chemically designated dl 2-(0-chlorophenyl)-2 (methylamino) cyclohexanone hydrochloride.
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Ketalar should not be used if the solution is coloured and/or contains particulate matter. 6.5 Nature and Contents of Container. Ketalar 200 mg (base)/2 mL, 5 x 2 mL glass vials. 6.6 Special Precautions for Disposal. In Australia, any unused medicine or waste material should be disposed of in accordance with local requirements.
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Ketalar may cause serious side effects. Call your doctor at once if you have: painful or difficult urination, increased urination, loss of bladder control, blood in your urine; a light-headed feeling, like you might pass out; slow heart rate, weak or shallow breathing; or. jerky muscle movements that may look like convulsions.
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KETALAR contains the active ingredient ketamine hydrochloride. KETALAR belongs to a group of medicines called anaesthetics and is used to make the body insensitive to surgical treatment. It may be used in combination with other medicines to induce anaesthesia. For more information, see Section 1. Why am I being treated with KETALAR? in the full.
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2. Ketalar Dosage and Administration. 2.1 Important Dosage and Administration Information KETALAR should be administered by or under the direction of physicians experienced in the administration of general anesthetics, maintenance of a patent airway, and oxygenation and ventilation. Continuously monitor vital signs in patients receiving KETALAR.
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The onset of action of KETALAR is rapid; an intravenous dose of 2 mg/kg of body weight usually produces surgical anaesthesia within 30 seconds after injection, with the anaesthetic effect usually lasting 5 to 10 minutes. If a longer effect is desired, additional increments can be administered intravenously or intramuscularly.
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Ketalar 10mg/ml contains 53 mg of sodium per 20 ml of solution. For the full list of excipients see section 6.1. 3. Pharmaceutical form. An intravenous dose of 2 mg/kg of bodyweight usually produces surgical anaesthesia within 30 seconds after injection and the anaesthetic effect usually lasts 5 to 10 minutes. An intramuscular dose of 10 mg.
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When fluid restriction is required, KETALAR can be added to a 250 mL infusion as described above to provide a KETALAR concentration of 2 mg/mL. KETALAR 10 mg/mL vials are not recommended for dilution. 3 DOSAGE FORMS AND STRENGTHS. KETALAR injection is a clear, colorless, sterile solution available in multiple-dose vials containing.
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Ketalar 10mg/ml Solution for Injection/Infusion. Pfizer Healthcare Ireland PA0822/013/001. Main Information.. Kevin O'Malley House, Earlsfort Centre, Earlsfort Terrace, Dublin 2, Ireland, D02 XP77 +353 (1) 676 4971; [email protected] Follow @TheHPRA . Developed by Engine Solutions.
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Ketalar is used in adults, the elderly and children. Ketalar can be given alone or in combination with other anaesthetic agents. 2. What you need to know before you are given Ketalar Injection Do not take Ketalar: • if you are allergic to ketamine hydrochloride or any of the other ingredients of this medicine (listed in section 6).
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Ketalar n'est pas indiqué ni recommandé pour une utilisation à long terme (voir rubriques 4.1 et 4.2). Des cas de cystite, y compris des cystites hémorragiques, d'insuffisance rénale aiguë, d'hydronéphrose et de troubles urétéraux ont été rapportés chez des patients utilisant le Ketalar durant une longue période, en particulier en cas d'abus de kétamine.
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Coadministration with other CNS depressants, such as skeletal muscle relaxants, may cause respiratory depression, hypotension, profound sedation, coma, and/or death. Consider dose reduction of either or both agents to avoid serious adverse effects. Monitor for hypotension, respiratory depression, and profound sedation.
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Ketalar is recommended: 1. as the sole anaesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. Ketalar is best suited for short procedures and it can be used with additional doses, for longer procedures; 2. for the induction of anaesthesia prior to the administration of other general anaesthetic agents, and 3. to supplement low-potency agents.
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KETALAR 200 mg/2 mL, 5 x 2 mL vials. Australian Registration Number: AUST R 70073. Who distributes KETALAR. Pfizer Australia Pty Ltd. Sydney NSW. Toll Free Number: 1800 675 229.
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DESCRIPTION. Ketalar is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injection in concentrations containing the equivalent of either 10, 50 or 100 mg ketamine base per milliliter and contains not more than 0.1 mg/mL Phemerol.